Breast Cancer Treatment Drugs
Breast cancer mainly develops due to the abnormal growth of certain cells in the breast. The cancer of breast occurs when a mutation or abnormal change occurs that upsets how breast cells multiply and divide. There are more chances of spreading the breast cancer to other parts of the body.
The cancer of the breast commonly develops in cells from the lining of milk ducts and the lobules that supply these ducts with milk. A cancers that developed from the ducts are known as ductal carcinomas, while those developed from lobules are called lobular carcinomas. For diagnosis of breast cancer, doctors simply take a biopsy of the concerning tissue for confirmation. And once the diagnosis is done, with the help of further tests it is easy to determine if the cancer has spread beyond the breast and which treatments are most likely to be effective for the patient with breast cancer.
There are some risk factors which may be responsible, factors such as being female,lack of exercise, obesity, alcohol, hormone replacement therapy during menopause, ionizing radiation, early age at first menstruation, having children very late in the life or sometimes not at all, older age, prior breast cancer, family history of breast cancer, Klinefelter syndrome.
Breast Cancer Treatment with Palbociclib: The FDA approved Palbociclib medication is used in combination with an aromatase inhibitor to treat advanced-stage or metastatic, hormone-receptor-positive, HER2-negative breast cancer that hasn’t been treated with hormonal therapy before in postmenopausal women and men.
Ibrance 125 mg also is approved to be used in combination with Faslodex (fulvestrant) in order to treat advanced-stage or metastatic, hormone-receptor-positive, HER2-negative breast cancer that has grown after being treated with hormonal therapy in women and men. Women with premenopausal and perimenopausal, who take this medication (Ibrance) in combination with Faslodex also should be treated with a medicine to suppress ovarian function.
Patients taking palbociclib 125 mg may experience a condition named neutropenia. In this condition patients has an abnormally low number of neutrophils.
Other side effects may include infection, leukopenia, anemia, fatigue, headache, anemia and decreased appetite as well. In circumstances of any side effects, immediately ask for help from your healthcare providers.
How Palbociclib Works: It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.In the G1 phase of the cell cycle, mammalian cells must pass a checkpoint, known as the restriction point "R", in order to complete the cell cycle and divide. CDK4 as well as CDK6 complex with cyclin D drive the phosphorylation of the retinoblastoma protein, Rb, which allows the cell to pass R and commit to division. Regulation of one or more proteins involved in this checkpoint is lost in many cancers.
After inhibiting CDK4/6, palbociclib ensures that the cyclin D-CDK4/6 complex cannot aid in phosphorylating Rb. This resists as well as prevents the cell from passing R and exiting G1, and in turn from proceeding through the cell cycle.
Price of Palbociclib: The price of Palbociclib is very economical as well as affordable for all the patients with breast cancer.
A patient can easily purchase this breast cancer medication from any registered pharmaceutical company after being prescribed by their doctor.
Breast Cancer Medication List: Medical treatment for breast cancer involves following enlisted medications which are some way related to or used in the treatment of patients with breast cancer.
Anastrozole (Brand name - Arimidex)
Tamoxifen ( Brand Name - Soltamox)
Exemestane ( Brand Name- Aromasin)
Methotrexate (Brand Name- Trexall)
Doxorubicin (Brand Name - Adriamycin)
Paclitaxel ( Brand Name - Taxol)
Capecitabine (Brand Name - Xeloda)
Everolimus ( Brand Name - Afinitor)
Ribociclib ( Brand Name - Kisqali)
Trastuzumab-hertraz 440 mg injection(Brand Name - Hertraz)
