What is Venetoclax?
Venetoclax (Brand Name Venclexta), specifically used in order to treat adult patients with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), or acute myeloid leukemia (AML).
How does Venetoclax work?
Venetoclax works by blocking a protein in the body named BCL-2. This is a kind of protein that helps cancerous cells survive. Blocking this protein helps to destroy as well as reduce the number of cancerous cells.
In what dosage form Venclexta comes: This medication comes in the following dosage forms: Tablets of Venetoclax 10 mg, 50 mg, and 100 mg.
How to take Venetoclax?
Always consume it exactly as your healthcare professional tells you. You should drink plenty of water when taking venetoclax in order to help reduce your risk of getting TLS. Consume the tablets with a meal and water at about the same time each day. Swallow venetoclax tablets whole. Chewing, crushing, or breaking the tablets is not recommended
What are possible side effects from using Venetoclax?
- Itching
- Diarrhea
- Constipation
- Nausea
- Vomiting
- Decreased appetite
- Weight loss
- Stomach pain
- Weakness
- Mouth sores
- Shortness of breath
- Rash
- Fever
- Headache
- Dizziness
- Feeling tired
- Cough
- Swelling of arms/legs/hands/feet
- Muscle/back/bone/neck and joint pain
The venclexta uses are responsible for causing abnormal exams as well as blood test results. Your healthcare practitioner will perform some tests prior to and during the treatment.
Overdose: In case you think you have consumed too much venetoclax 100mg, contact your healthcare team, hospital emergency department right away, even if there are no symptoms.
Missed dose: In case it has been less than 8 hours, consume your dose right away. In case it has been over 8 hours, you should skip the forgotten/missed dose and should consume the next dose at your usual time the next day.
In case you vomit following taking venclexta 100mg or any other strength, avoid consuming an extra dose. Consume the next dose at about your usual time the next day.
Storage: Store Venetoclax tablets between 2 and 30°C. Keep out of reach as well as sight of the children.
Drugs Approved for Chronic Lymphocytic Leukemia (CLL): Apart from Venclexta (Venetoclax), there are several other chronic lymphocytic leukaemia medicines given as follows:
- Arzerra (Ofatumumab)
- Bendeka (Bendamustine Hydrochloride)
- Calquence (Acalabrutinib)
- Campath (Alemtuzumab)
- Copiktra (Duvelisib)
- Cyclophosphamide
- Dexamethasone
- Fludarabine Phosphate
- Gazyva (Obinutuzumab)
- Imbruvica (Ibrutinib)
- Leukeran (Chlorambucil)
- Prednisone
- Rituxan (Rituximab)
- Rituxan Hycela
- Zydelig (Idelalisib)
NOTE: The information provided in this article is only for informational purposes and is not served as a substitute for the medical treatment, consultation, diagnosis, of a qualified healthcare practitioner.
FAQ's
Is Venetoclax a chemotherapy?
Venclexta (venetoclax) falls under a type of targeted treatment rather than chemotherapy.
How long do you take Venetoclax?
In the form of tablets, venetoclax should be taken once daily with a meal. You'll be prescribed a low dose of venetoclax and then the dose is gradually increased over the initial 5 weeks of the treatment. This helps in order to reduce the number of CLL cells gradually.
How long does venetoclax take to work?
Venclexta usually starts to work within a few hours following having your first dose. You probably won’t notice it working, unless you have symptoms of tumor lysis syndrome (TLS).
Your healthcare practitioner will perform blood tests during your treatment in order to check that Venclexta is working for you.
What are the symptoms of end stage CLL?
- Early on, there are no chronic lymphocytic leukaemia symptoms, but later symptoms may include:
- Non-painful lymph node
- Feeling tired
- Fever
- Night sweats
- Weight loss
- Enlargement of the spleen
- Low red blood cells (anemia)
- These symptoms typically worsens gradually over years.
How long can you live with CLL (chronic lymphocytic leukemia)?
On average, patients with this cancer survive 9 years, although some have lived for decades, cancer always comes back at some point.
Is Venetoclax available in India?
Yes, there are some WHO-GDP & ISO certified pharmaceutical wholesalers companies that can source Venclexta (Chronic lymphocytic leukaemia Treatment Medicine) from across the globe, and have the ability to supply.
Where can I get Venclexta?
In India, you can get Venclexta at the very best price simply by choosing any reliable pharmaceutical wholesaler company such as www.indianpharmanetwork.in & theindianpharma.com.
How much does Venetoclax cost?
The price of Venetoclax may vary from generic to innovator drugs. Visit above mentioned websites in order to get the Venetoclax price.
