Trientine hydrochloride
Wilson’s disease is a type of genetic disorder, in which the body builds up unnecessary and excess copper. This disease caused by a mutation in the Wilson Disease protein gene (ATP7B). This protein transports the excess copper into bile.
Symptoms could be directly related to the liver and brain. Patients with Wilson`s disease may experience a few signs and symptoms such as Weakness, Swelling in the legs, fluid build-up in the abdomen and vomiting, muscle stiffness, tremors, difficulty in speaking Etc.
Wilson's Disease Eye: (KF rings) Kayser–Fleischer rings, a pathognomonic indication, could appear in the Cornea of the eyes, Whenever excess deposition of copper occurs in the Descemet`s membrane, this disease takes place in the shape of a ring around the cornea of eyes. This disease not hit to all the people with Wilson`s Disease.
Symptoms of Wilson`s Disease:
People who have diagnosed with Wilson`s disease may feel symptoms related to the liver as well as some terms related to brain disease.
Liver-Related symptoms: Liver-related symptoms could occur as:
• Vomiting
• Itchiness
• Weakness
• Yellowish Skin
• Swelling in the Legs
• Fluid Build Up in the Abdomen
Brain-Related Symptoms: Symptoms related to the brain may appear as:
• Anxiety
• Tremors
• Muscle Stiffness
• Personality Change
• Difficulty in Speaking
People with a family history are more likely to get Wilson`s Disease. This disease is genetically based.
Diagnosis of Wilson Disease:
This disease can be detected based on the symptoms which are mentioned above. Also, there are some other ways by which the doctor used to detect the diagnosis of this disease. The diagnosis of Wilson disease may possible with the help of Liver Biopsy, Genetic testing, and Ceruloplasmin.
Treatment: Treatment of Wilson`s Disease is possible in a few ways including medication and dietary containing less copper.
Low-level Copper Containing Food:
By planning the diet which contains a low level of copper would be effect full against this disease. A low-level copper-containing diet gradually absorbs the excess quantity of the copper. Thus, dietary including Mushroom, Dry Fruits, Shellfish, Chocolates, Sesame Seeds as well Sesame Oil helps to get rid of the Wilson`s Disease.
FDA approved Medications:
FDA has approved some medication for the treatment of Wilson`s Disease. These medications are the first choice of treatment in order to treat Wilson`s Disease. Trientine hydrochloride medication is popular amongst physicians.
Trientine Hydrochloride:
Trientine is a generic of the brand name of Spyrine. This medication works by eliminating the excess copper from the body in the patients who intolerant to penicillamine.
Some very rare side effects may occur due to this medication which is enlisted as Heartburn, Stomach Pain, General Ill feeling, Mouth Sores and Loss of Appetite Etc. Immediately seek help if you feel any elaborated signs and symptoms.
How to Use Trientine 250 mg capsules:
The dose of this medication (syprine 250 mg) totally depends on your physician. Take this medication under the guidance of your doctor for better outcomes.
If you experience any side effects due to this medication, contact your doctor on an urgent basis.
The cost of this medication is quite economical because of its generic properties. You can buy this medication online from any genuine pharmaceutical firm/company.
