ALS Disease Treatment
What is Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a neurological disease that affects the nerve cells which are responsible for controlling voluntary muscle movement. Voluntary movements include talking, chewing, and walking.
The signals in the human body are initiated from motor neurons in the brain generally called as upper motor neurons are transmitted to motor neurons present in the spinal cord, which is further transferred to motor nuclei of the brain basically called as lower motor neurons and from this neuron the message is specifically carried to muscles.
In this disorder, the upper motor neurons, as well as lower motor neurons, degenerate and die thus stopping sending messages to muscles. Ultimately the brain loses its ability to send signals and initial voluntary movements.
ALS is a neuromuscular disorder that can be caused randomly. However few risk factors are:
● Age: The men age 55 to 75 are having a high risk of this disease.
● Race and ethnicity: Caucasians and non-Hispanics are at high risk of this disease.
● Gender: Men have more risk to develop ALS.
Amyotrophic lateral sclerosis symptoms: Some early symptoms of this disorder include:
● Difficulty chewing or swallowing.
● Muscle cramps
● Difficulty in nasal speech
● fasciculations in arms
● Stiff and tight muscles.
● Difficulty in writing
● Pain in walking
● A problem in speaking (dysarthria), swallowing (dysphagia), and breathing (dyspnea).
Regardless of the fact that where the first symptoms appear, the weakness and muscle pain is felt all over the body. The patient suffering from ALS has difficulty in chewing and swallowing the food thus leading to faster weight loss as compared to normal people.
How to diagnose (ALS) amyotrophic lateral sclerosis: No test can confirm the presence of amyotrophic lateral sclerosis. Generally, a doctor examines by checking the signs and symptoms of ALS.
However several diagnostic methods can detect the presence of disorder to some extent. These are:
● Muscle and imaging tests: This technique is used to detect the presence of electrical activity of muscle fibers.
● Nerve conduction study (NCS): This technique works by sending an electrical signal via neurons to muscles.
● Laboratory test: Blood or urine test is done to detect the presence of this disorder.
Amyotrophic lateral sclerosis Treatment: No cure for this disorder has been discovered till date. However few treatment medications are used to reduce the symptoms and avoid complications.
Some treatment options are:
● Physical therapy: This therapy basically includes stretching of muscles and activities such as walking, swimming, and running.
● Speech therapy: Patients suffering from the problem of speaking may take speech therapy to improve the ability to speak.
● Nutritional support: It has been seen that patients with a low nutrition diet may have a high degradation of this sclerosis.
● Medication: The US food and drug administration approved the drugs edaravone (Radicava injection) and riluzole (Rilutek). Edaravone 30mg slows the daily decline in patient health suffering from ALS. radicava 30 mg is available to help patients suffering from constipation, sleep disorder, and depression
Riluzole reduces the level of glutamate which is responsible for transporting messages between the motor neuron and nerve cell.
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